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Jama 323 , 2324 (2020)

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Lead binds to thiol groups, and may therefore inactivate GSH as well as other enzymes with functional thiol groups, and has been shown to increase homocysteine levels (see below for homocysteine)

The elution profile of the sample homogenized in BSAN buffer (blue tracing) is characterized by the presence of both the two symmetrical peaks corresponding to the GS-NEM conjugate (4.29 min and 4.95 min r.t.) and the peak corresponding to the excess of NEM (5.8 min r.t.)

[DOI] [PubMed] [Google Scholar] Jang JH, Surh YJ