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Parallel ultrastructural analysis of normal human fibroblasts showed a typical spindle-like shape and a cytoplasm with a few rough endoplasmic reticulum cisternae and intracellular filaments (Fig

M.EricksonD.MoldwinR.FaradayM

Front Cell Infect Microbiol 12:1023806

Dihydroorotate dehydrogenase (DHODH), a mitochondrial enzyme located on the outer surface of the mitochondrial inner membrane, plays a crucial role in this process