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It was rare at the beginning of the century, but then decade after decade it became steadily more common

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Microtubule-associated protein-1 light chain-3 (MAP1LC3), abbreviated as LC3, is a subfamily of the autophagy-related gene 8 (Atg8) family in eukaryotes, which includes LC3A, LC3B, LC3B2, and LC3C (Shpilka et al., 2011)

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