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Pathological effects generally arise only when the mutant load exceeds a threshold [162]

Resveratrol, a known activator of SIRT1, reduced TSA-mediated acetylation and ubiquitination of SOX2, thereby enhancing the colony-forming ability as well as osteogenic and adipogenic differentiation of BM-MSCs in a dose-dependent manner

10.1016/j.ejogrb.2014.10.041 159

Depletion of mitochondrial GSH is associated with cellular senescence, compromised energy production, and age-related pathology (910)

Introduction Glutamate is one of the main excitatory neurotransmitters of the CNS, contributing to normal neural transmission, development, differentiation, and plasticity

The pivotal role of the placenta in normal and pathological pregnancies: A focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease