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Similarly, intranasal antibodies targeting A have reduced cerebral amyloid burden and improved cognition in preclinical models (Xiao et al., 2013)

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The gut microbiota of ADHD patients was transferred to mice by researchers and found that the structural integrity of white matter and gray matter regions (such as the internal capsule and hippocampus) in the mice was lower, and there was a significant correlation between the structural integrity of white matter and the differentially expressed microbial community (34)

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