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Description

Electroacupuncture at the Tianshu (ST25) point can alleviate PD-associated constipation by enhancing the autophagic state within the enteric nervous system, protecting enteric neuronal function, and regulating intestinal motility

Hepatology 65 , 529543 (2017)

Animals were sacrificed under xylazine/rompun anesthesia, and every effort was made to minimize animal suffering

This implies that a potential drug candidate could be dismissed based on its elevated expulsion rate from the brain in rodent models when, in reality, this observation may not necessarily hold true in clinical settings