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The calcium-binding affinity of S100 proteins is low in the absence of target proteins, but the affinity is significantly increased by several orders of magnitude in the presence of specific target proteins (35, 36)

This applies to women with pattern hair loss or diffuse thinning, for whom dutasteride is not an option

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Any actual application of peptides in a companion animal context should be evaluated by a licensed veterinarian who can assess the individual animal, set appropriate dosing, and monitor for adverse effects

robust human dose-finding data remain limited

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