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Serine-dependent sphingolipid synthesis is a metabolic liability of aneuploid cells

PMID: 31 ZhangXQiMHuoKCaiBZhangJTianYet al

Addition of a gastrointestinal microbiome modulator to metformin improves metformin tolerance and fasting glucose levels

H.JayakumarT.LuW

The incidences of ALT and AST increases were 37% and 22%, respectively, in the omaveloxolone arm versus 2% each in the placebo arm (Table 1) [16, 20, 22]