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Neuro-Psychopharmacology Biol

Chromium: insulin potentiation and metabolic regulation The chromium element, especially the trivalent variant chromium picolinate, plays an important role in augmenting the action of insulin by stimulating receptor activity

Cell 71, 398408

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Further, the substrate (2-ketoglutarate) is stabilized through Lys114 and Lys102 on one carboxyl terminal and Lys78 and Arg193 on the other terminal, forming a salt-bridge interaction (Fig