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Furthermore, petroleum ether, ethyl acetate, and ethanol extracts exhibited EC 50 lower than the positive controls butylated hydroxytoluene (BHT) and ethylenediaminetetraacetic acid (EDTA)

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Lonidamine (LND, Figure S1A), an indazole-3-carboxylic acid derivative, specifically inhibits aerobic glycolysis and energy consumption in neoplastic cells [30]