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A holistic approach in the framework of 3P medicine

(2020) 183:636649.e18

The increased serum concentration of 5-HT and the simultaneously decreased excretion of 5-HIAA can be attributed to the decreased activity of MAO (50, 54, 56)

On the basis of Model 2, chronic comorbidities (diabetes, hypertension, coronary heart disease, and stroke) were added to Model 3 as a comprehensive adjustment of covariates, and the adjusted results showed that the inverse association between dietary niacin and PD risk remained stable

213,214 This would trigger the subsequent mtDNA-cGAS-STING pathway, activating the downstream inflammatory response

Zn supplementation improves osmolytes accumulation and expression of stress-responsive genes and brings ultra-structure changes in the plant body to counter the effects of HMs