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Guha, N., Cowan, D.A., Sonksen, P.H

Most proinflammatory cytokines such as IL-6, IL-1, TNF-, IL-8, and IFN as well as some anti-inflammatory mediators including -aminoisobutyric acid, A20 enzyme, and EPO have been shown to impair adipogenesis, leading to adipocyte hypertrophy, ectopic fat accumulation, and increased risk of IR and T2DM

Among them, 34 are novel sulfur-containing compounds, including two dimers ISA 2 -S (13,13-thiobis (11,13-dihydroisoalantolactone)) and ISA 2 -SS (13,13-dithiobis (11,13-dihydroisoalantolactone)) (Yao et al., 2017)

13:e1006712

The present results demonstrated that Klotho protein significantly contributed to inhibition of the IGF1R/PI3K/AKT signalling during heart IRI

1 Treatment-resistant depression in females and those with a history of childhood trauma had the lowest documented levels of L-Carnitine