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The glucosinolate glucoraphanin of broccoli sprouts interacts with myrosinase to produce the phytochemical sulforaphane (SFN) (Figure 6)

Other mechanisms slow sperm aging

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The functional mechanisms of NRF2 involve multiple levels, comprehensively regulating the cellular response to oxidative stress

Thus, prospect studies should be geared towards using nanoparticles to engineer and transport antioxidants such as vitamin E, selenium, or quercetin directly to sperm cells or their mitochondria to enhance their effectiveness on protection compared to traditional methods (Tiwari et al., 2022)