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M1 and M2 macrophage phenotypes A classification system in which heterogeneous macrophages are grouped as either M1, which defines activated pro-inflammatory macrophages associated with protection against bacteria and viruses, and M2, which are alternatively activated macrophages that express different markers and are associated with wound healing and immune suppression

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Under each of these constraints, the maximal production of reduced GSH in the model was computed

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The granules of mast cells contain a variety of highly active mediators, including histamine, prostaglandins, leukotrienes, heparin, serotonin, inflammatory cytokines (such as IL-6, TNF-, MCP-1, etc.), and neutral proteases