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BCAT1E61A's higher enzymatic activity can promote the catabolism of BCAA and accelerate cell growth and metastasis, and BCAT1 can also activate the PI3K/AKT/mTOR pathway to contribute to the development of tumors [40]

For both metabolomics and tracing experiments, treated CD8 + T cells were collected and washed with cold saline solution twice in 15 mL tubes

Our GO term enrichment studies in the hepatocytes comparing BWS to nonBWS liver demonstrated an enrichment of fatty acid and lipid metabolic pathways in BWS hepatocytes, indicative of PPARA involvement in the dysregulation of these processes in BWS liver

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