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That means three things in practice

The data indicate that the hydrogen bonds formed in this binding mode are not very reliable, and the fluctuations in the RMSD during the latter part of the simulation confirm the instability of CME_c

Capmatinib can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5

[] In this case, despite three surgeries and prolonged local wound care, the abdominal incision failed to close spontaneously, requiring a definitive fistula resection

Available from: [DOI] [PubMed] [Google Scholar] 163.Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ

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