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Intestinal epithelial cell injury due to ionizing radiation-induced ferroptosis is effectively abrogated by the iron chelator deferoxamine in vitro and in vivo

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483 Caloric limitation, intermittent fasting and specific amino acid restriction are all found to be able to extend lifespan

Basal OCR was determined by subtracting rotenone and antimycin A (Sigma-Aldrich, A8674) insensitive oxygen consumption from baseline measurements

Sequential treatment strategies, such as using LNP mRNA for rapid protein replacement followed by AAV for long-term correction, may be particularly suitable for pediatric patients to avoid the dilution effect of AAV vector genomes in proliferating liver cells [353]

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