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Parts of this work were funded by grants from the DFG (German Research Foundation)Projektnummer 209933838SFB 1052 (project B1 to M.B.) and by Deutsches Zentrum fr Diabetesforschung (DZD, Grant: 82DZD00601 to M.B.)

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[1] This article reveals the molecular recognition of morphine and fentanyl by the human -opioid receptors, and proposes an analog design based on the structure of fentanyl to weaken the -arrestin activity of OR

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