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PDA in premature infants may need indomethacin treatment (in the first 2-4 weeks of life) or surgical ligation

This is the way, how Mecobalamin, Niacinamide & Pyridoxine Hydrochloride Injection treat vitamin b12 deficiency, anaemia, and also infection which are caused by bacteria

PLoS One 16 , e0259900 (2021)

[DOI] [PubMed] [Google Scholar] 161.Iles MM, Law MH, Stacey SN, et al

Their interaction is mainly manifested in shared metabolic hubs, a common platform for organellar stress, and overlapping upstream regulatory pathways