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At the tested concentrations, no significant interference of tested compounds with any of the used assays was observed

Redox Biol 24:115

However, the LES competence can be difficult to assess preoperatively, because esophageal manometry can be unreliable in the presence of PEH [73]

This master antioxidant plays a vital role in nutrient metabolism, antioxidant defence, and regulation of cellular activities such as protein synthesis and immune response

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The statistically significant increase in the GSH:GSSG ratio in cases vs controls, despite this apparent artifact if it has happened, suggests that the changes in the glutathione redox status are robust and could be detected despite this experimental anomaly