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doi: 10.1074/jbc.M304987200 149 RoachT.Krieger-LiszkayA

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These variants equally preserved their GSH-transferase activity, suggesting the importance of additional factors in the modulation of the negative log of GSHs acid dissociation constant (p K a ), including the ability to optimally arrange the well-described electron-sharing network which generates a positively charged electrostatic field in the G-site of GSTs 40,41

This is referred to as sensory gating and it helps stop the perception of phantom sounds despite ongoing neural activity in the hearing nerve

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doi: 10.1182/blood-2018-03-784116 7 Selimoglu-BuetDBadaouiBBenayounETomaAFenauxPQuesnelBet al