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As research advances in the future, this mitochondria-targeted drug holds promise to transition from the laboratory to clinical practice, offering new hope for delaying disease progression and improving the quality of life for a wide range of patients

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Both strategies are proving far more effective than single-target GLP-1 agonism

The -KG carrier (encoded by SLC25A11 ) and the dicarboxylate transport mechanisms (dicarboxylate carrier, encoded by SLC25A10 ) are two potential candidates for importing cytosolic GSH to the mitochondria, mainly in the kidney and liver

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These peptides exhibited potent ACE-inhibitory activity (IC50: 37.0658.72 M) and hydroxyl radical scavenging capacity (IC50: 70.8495.23 M)