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Tau protein is important for maintaining the stability of axonal microtubules involved in the mediation of fast axonal transport of synaptic constituents

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Metformin attenuates osteoclast-mediated abnormal subchondral bone remodeling and alleviates osteoarthritis via AMPK/NF-kappaB/ERK signaling pathway

In the high-dose treatment group, they reported statistically significant improvements in the total score, the motor subscore, and the non-motor subscore

The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method

In an inflammatory setting induced by IL-1, increased levels of hypoxia-inducible factor-2 (HIF-2) coupled with diminished GPX4 expression in chondrocytes increase their susceptibility to ferroptosis ( Figure 4 ) (80, 161)