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This influence may be at least partly related to oxidative stress, since smoking habit decreases factors related to antioxidant capacity, such as uric acid 5

Shaking the vial creates shearing forces that can physically break the delicate amino acid bonds of the peptide, a process called denaturation

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The Category 2 designation was not a finding that BPC-157 is dangerous per se, but rather that insufficient human safety data exists to justify its use in compounded medications without the oversight of the standard drug approval process

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