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Unfortunately, most of the screening methods used were in vitro and have only led to the identification of compounds with relatively low potency and limited selectivity (Thorson et al., 2013, 2015

EMBO J 17 : 25962606

Ill do that with patients that have rheumatoid factor issues, or people that are very sensitive to lectins

Whether the myelination observed in tNs across these different environments recapitulates the exquisite diversity and specificity of the myelin patterns from the host cortical circuits has not yet been explored