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Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 19851995, using the National Cancer Database

Myelosuppression leading to low platelets increases the risk of excessive bleeding (Carey 2003

This ultimately leads to an elevated CD4+/CD8+ ratio (176)

The mechanism of this effect is via upregulating the SOCS-2 protein which in turn inhibits the JAK1-STAT5 signal transduction pathway of the GHR (371)