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In the case of the colitis-associated cancer (CAC) mouse model, IKK genetic deletion in intestinal epithelial cells greatly reduces the incidence of tumors through the increase of apoptosis [52], while its KO in the macrophage significantly reduces tumor size by suppressing the expression of pro-inflammatory factors [53, 54]

Synthesis of essential molecules Magnesium is required for a number of steps during synthesis of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and proteins