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In a human trial, injections of autologous expanded bone marrow MSCs into the NP resulted in elevation of water content and rapid improvement of pain (Orozco et al., 2011)

According to a previous analysis of tear fluid from 18 normal controls and 36 PD patients using mass spectrometry, PD patients had considerably greater amounts of 21 proteins and lower levels of 19 proteins than those of the normal subjects

Unlike an acute inflammatory response designed to eliminate a threat and return to baseline, CIRS involves prolonged activation of innate immune pathways