It may be due to: A weakness in your immune system (for example, from the cold or flu) Hormone changes Stress Lack of certain vitamins and minerals in the diet, including vitamin B12 or folate Less commonly, mouth sores can be a sign of an illness, tumor, or reaction to a medicine
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When the virus is reactivated, whether by stress, illness, or sun exposure, it travels back along the same nerve pathway to the surface of your skin
Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63
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