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CYT-6091 clinical trials started in 2005 for delivery of recombinant TNF- as an anticancer therapy in late-stage pancreatic, breast, colon, melanoma, sarcoma and lung cancer patients

Liver fibrosis occurs through dysregulation of MyD88-dependent innate b-cell activity

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As seen in Figure 1B, administration of atazanavir to normal human individuals was associated with a decrease in the proportion of bilirubin conjugates in the serum, suggesting that it was inhibiting bilirubin conjugation