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Description

8 To continue clinical trials, preclinical data including the efficacy, toxicity, and pharmacokinetics of panduratin A are necessary

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Most events were transient and occurred during dose escalation

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Antioxidant effects : Copper acts as antioxidant, protects cells from oxidative damage, enhances cellular repair

[Note: Four weeks was selected as the optimal time point representing advanced disease because our previous experience with this model has demonstrated that at 4 weeks, primary tumours are well established, and the cancer has metastasised