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While elevated MMA blood concentration is considered the specific indicator of deficiency (19), other clinical assays are often used as biomarkers of vitamin B 12 status sometimes in combination

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However, conventional (primed) human iPSCs rely minimally on FAO for energy or acetyl-CoA production 24 , and chemically modulating FAO in primed hPSCs has little effect on pluripotency markers 23

These free radicals can damage other cellular structures such as proteins, lipids, and DNA

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