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Combining steady-state kinetic monitoring with computational modeling is widely used to study metabolic changes and identify potential therapeutic targets

doi: 10.1016/j.abb.2019.108193, 176

Zheng XX, Li YC, Yang KL, He ZX, Wang ZL, Wang X, et al

& Uhlemann, A

However, the different kinetics of their induction and the distinct consequences of inhibition of the endogenous miRNAs suggest that miR-4488 may tame the proinflammatory response already at low levels of stress, whereas miR-4734 restricts the proinflammatory response only at a higher threshold