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Employing a higher value for the threshold factor k would impose a more stringent selection criterion, preferentially identifying reactions with the strongest linear correlation (R) between flux and predictive contribution

-glutamylcysteine exhibits anti-inflammatory effects by increasing cellular glutathione level

The extrinsic pathway involves interaction of cell surface death receptors [for example, Fas/CD95

& Pennefather, P

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Construction and selection of plasmids for spike-in controls Due to length constraints the protocol for the construction and selection of spike-in controls was moved to the Supplementary MethodsConstruction and selection of plasmids for spike-in controls