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One of the more commonly used methods to induce disc degeneration in recent studies has been the needle puncture injury method in both in vivo and ex vivo small and large animal models, where the IVD is punctured using needles of various gauges (Korecki et al., 2008

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The HOMA-IR was calculated using the formula HOMA-IR = fasting glucose (mg/dl) fasting insulin (U/ml)/405

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By amplifying the effects of HGF, it supports cellular processes critical for brain repair and functional improvement