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BMI1 promotes cell cycle progression and regulates senescence by acting as a transcriptional repressor at the INK4a/ARF locus [58]

In fact, a study found that older individuals experienced a 30% decline in glutathione levels compared to their younger counterparts

doi: 10.1007/s11033-025-11223-6, 49

There are three simple steps you can take to help overcome this gene mutation and minimize its effects

Murphy RA, Mourtzakis M, Chu QS, et al

Additionally, research indicated that there may be a reduction in the expression of urea cycle enzymes, a possible re-establishment of nitrogen balance, and a potential modification or enhancement of nitrogen levels in different tissues