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Moreover, in an in vitro model of blast-induced auditory hair cell damage, 3-AB inhibition of PARP1 reduced oxidative stress markers, upregulated antioxidant defenses, and helped maintain cell viability by preserving ATP pools 175

polygyrus ES products and recombinant protein, TGF mimic (TGM), showed some benefit in DSS-induced and TNBA-induced colitis, with a reduction in inflammatory cytokines [180,181]

Glycation In addition to oxidative stress, studies have uncovered a causative role for another modification, known as glycation , in the opacification of the lens (Swamy 1987)

In addition, the use of bacteria as carriers to deliver drugs to tumors and other lesions, or to modify bacteria to express or deliver targeted drugs will greatly improve the therapeutic effect (39, 45, 46)

Nutrients 15:3627 Shahini A, Shahini A (2023) Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome

SW, SJ, TM, JW, SH, JT, PT, and SC contributed to the data acquisition and data analysis, and interpretation