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In the present study, TLR4 exhibited no difference (TLR4: SMD: 2.38, 95%CI 0.61, 4.15, p=0.009) between the healthy control and mice induced with DCM probably given the small sample size, but there was high elevation of the AGEs (AGEs: SMD: 5.43, 95%CI 1.73, 9.13, p = 0.004) ( Supplementary Figure S1 - 1