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The main metabolite of nicotine metabolism is cotinine, in addition to this, nicotine is extensively metabolized by the liver into other metabolites like 5 hydroxy cotinine, 5 hydroxy nicotine, nornicotine and nicotine iminium ion etc., (Figure 10)

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As mentioned, seeking support from healthcare professionals, support groups, or using smoking cessation aids can enhance the chances of successfully quitting

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