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Selenium enhances the bodys antioxidant capacity by participating in the synthesis of various selenoproteins, such as the glutathione peroxidase and thioredoxin reductase families

Dopamine-producing neurons are lost in Parkinson's disease, a neurodegenerative condition

For instance, deletion of one SOD allele in transgenic mice over-expressing -APP accelerated the onset of behavioural changes and A plaques in brain parenchyma, but increased the development of cerebrovascular amyloidosis, gliosis, and neuritic dystrophy

In a healthy brain, microglia maintain a dynamic balance between protective, anti-inflammatory functions and detrimental, pro-inflammatory signaling [1, 3, 4]

Amorphous solid dispersions, while improving solubility, have a natural tendency to transform into a more stable crystalline form over time, which can lead to a loss of the bioavailability benefit (153)