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McMurtrey also pioneered many new tissue engineering techniques for growing new 3D tissue structures from patients' own stem cells for both neurologic and orthopedic applications, and he continues to advance new research strategies for the future with unique combinations of stem cells, biomaterial scaffolding, and signaling factors for 3D tissue regeneration along with the most technologically advanced minimally-invasive 3D image-guided procedures

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However, observations suggest that in the brains of AD patients, increased angiogenesis may disrupt this negative feedback loop, leading to an imbalance between angiogenesis and vascular inhibition

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