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MSC transplantation improves cardiac function in MI and reduces cognitive deficits in VCI models

It is marketed as a dietary supplement for this reason, and is also used as adjuvant therapy for neuropathy and to improve glycemic control

Parnetti L, Gaiti A, Mecocci P, Cadini D, Senin U

Jul 2023;20(7):475-494

FDA Status and Practical Notes Tesamorelin is the only peptide in this group with FDA approval to reduce visceral fat tied to HIV-related lipodystrophy

These modifications have been hypothesized to play a crucial role in the diffusion of DNA damage response/senescence-associated secretory phenotype (DDR/SAPS) signaling to non-damaged surrounding cells during aging, suggesting that DDR/SASP signaling components may contribute to the development of novel therapeutic interventions against age-related diseases (Olivieri et al., 2015)