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This compound contains the first 29 amino acids of the naturally occurring GHRH molecule, which is the portion responsible for triggering growth hormone release from the pituitary gland

Interestingly, the brain retains Se longer than the other organs, highlighting the potential importance of Se in the central nervous system [46]

Nevertheless, the discovery of an extra-hepatic IGF-I production in the following years[18, 45], made it necessary to spand the conception of the GH/IGF-I axis, being well accepted nowadays that pituitary GH is able to induce IGF-I synthesis in both liver (~75%) and other tissues[23, 46, 47], which subsequently, is able to act in an endocrine/paracrine/autocrine manner

Horses with higher protein or calorie needs, such as growing horses, broodmares, or those on lower-quality forage, may benefit from the addition of a protein source like soybean meal or alfalfa pellets

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

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