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However, human studies show that a decrease in MOTS is differentially regulated in the skeletal muscle and plasma of healthy males during aging, suggesting that the changes in MOTS-c levels result from normal aging and do not indicate disease development (D'Souza et al., 2020)

Moreover, the UA transportersURAT1, GLUT9, and ABCG2play crucial roles in regulating UA levels, with dysfunctional transporters leading to abnormal serum UA levels, as observed in hypouricemia and hyperuricemia

(2022) 30:143549.e9

Currently, adverse events associated with vaccines are monitored through several mechanisms, including the pre-and postlicensure studies undertaken by vaccine manufacturers, the VAERS, and the CDCs large-linked database (LLDB)

PINK1 deficiency in -cells increases basal insulin secretion and improves glucose tolerance in mice