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The concept of selective insulin resistance is therefore critical for understanding the complex pathophysiology of T2DM, in which the insulin resistant state prevails in many tissues, but in a tissue-dependent, pathway-specific manner

Reticulocytosis (increased production of immature red blood cells) typically begins by day 3-4 of starting treatment, indicating active bone marrow recovery

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doi: 10.1016/j.celrep.2016.07.027

Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study