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Importantly, the lipid ROS generation byproduct malondialdehyde (MDA), recently validated as a specific in vivo marker for ferroptosis induction 66 , was increased in combo-treated tumors of both subtypes indicating in vivo induction of ferroptosis by combo treatment (Supplementary Fig

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The interaction between basal and dense fission in the posterior pallid amygdala can modulate motor behavior ( 3.1 The PFC-Hip-Amy circuit influences the development of neurological diseases In many neurodegenerative or injurious lesions, patients often present with decreased attention, spatial disorientation, memory loss, or abnormal postural control, which are significantly associated with abnormalities in the functional connectivity between the PFC-Hip-Amy circuits (Huang et al., 2016)

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Extensive studies have revealed that KARs adopt a Y-shaped architecture with four distinct layers: the amino-terminal domain (ATD), which is critical for receptor assembly