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119,131 Chelating Cu using d-penicillamine has also been reported to have beneficial effects in transgenic SOD1 mouse models, delaying disease progression and prolonging survival

doi: 10.1007/978-1-4020-2333-0_11 93 PessinaS.LenziL.PerazzolliM.CampaM.Dalla CostaL.UrsoS.et al

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doi: 10.1155/2021/5537330 116 BattagliaAMChirilloRAversaISaccoACostanzoFBiamonteF

Our aim was to examine if we, based on the collected information, could gain more insight into how chemicals induce these effects and use the information to elaborate more robust modes of action or Adverse Outcome Pathway frameworks ( Compounds With a Clear Dose Related Effect on Both NR and AGD Flutamide, vinclozolin and procymidone all have AR antagonistic activity, and all three show very marked anti-androgenic effects in vivo

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