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Author contributions This perspective was conceived by DD and AR

Absorption quotient between the two assay conditions was calculated by the following equation: Absorption quotient (AQ) = (Papp, A-B with inhibitor - Papp, A-B without inhibitor)/Papp, A-B with inhibitor where Papp, A-B with inhibitor and Papp, A-B without inhibitor represent the apparent permeability of test compound from the apical to basal side of the cellular monolayer in the presence and absence of 10 P-gp inhibitor GF120918, respectively

The lower availability of MOR in obese individuals may contribute to overeating as a way to compensate for reduced pleasure responses in this system

A peptide is simply a short chain of amino acids, too short to be called a protein

The incidence of SUDEP