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Key Insights Homeostasis is the Goal: Treatment should aim for balance (homeostasis), avoiding excessive stimulation that causes oxidative stress

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In accordance, antiTNF therapy has been shown to decrease glucose uptake and reduce the inflammatory response in RA joints 37,39

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This is why guidelines are moving towards lifetime risk calculators, personalisation of risk assessment, including the use of apoB and imaging scans as additional ways to individualise discussions around cardiovascular risks [8]