If your protocol involves a single administration or requires the entire vial to be used within three days, sterile water is acceptable, but for multi-dose protocols, bacteriostatic water is non-negotiable
Oxidative stressan imbalance between free radicals and antioxidants in your bodyand low amounts of vitamin E and alpha-lipoic acid can cause glutathione levels to decline (4)
Inhibition of tyrosinase (the key enzyme of melanogenesis): Direct inhibition: Thiol group binding with the copper-containing active site of the enzyme Indirect inactivation: Exerted via the antioxidant effect of glutathione that leads to quenching of free radicals and peroxides Switching production of eumelanin to phaeomelanin Modulation of the depigmenting properties of other antimelanogenic principles Table No * N * F * 100] / W Where VU = Titrant volume of sample (ml) Vb = Titrant volume of blank (ml) N = Titrant Normality F = Equivalence Factor W = Weight of Sample (mg) Acceptance Criteria: 98.0% - 101% on the dried basis
doi: 10.1002/jcph.1008 156 SmeyneMSmeyneRJ
Ethics declarations Human and animal rights and informed consent This article does not contain any studies with human or animal subjects performed by any of the authors
Patients should use supplements that meet BOMSS specifications and always follow the guidance of their bariatric dietitian or surgical team, as individual requirements vary based on blood test results and clinical assessment
